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Aloe Vera - Dosage, Interactions with Drugs and Risks

09 January, 2021

The Plant with Boons and Curses - Aloe Vera. Aloe yields two tangible elements i.e., the Latex and Aloe Gel. The Latex is the yellow-colored liquid-like substance found right under the skin of the Aloe Vera, primarily used as a Laxative. The Gel, found deep inside the Aloe Vera leaves by splitting them in two, is a translucent jelly-like substance which is thicker in consistency than that of the latex. The Gel is used for various purposes mainly for the skin.

Since Aloe Vera provides abundant medicinal privileges, it also has its share of complications and risks to offer.

Consumption and Dosage of Aloe Vera:

Aloe Vera is best used and consumed in decolorized and purified Form after all the impurities and aloins are extracted. Aloe Vera Gel is largely used in its raw and unprocessed form, domestically in homes for Skin and hair care for cosmetic usage. Many people who tend to consume raw Aloe Vera orally, being unaware of the risks it carries, often lands up at the doctor’s clinic. Hence, Topical Use (externally applied like an ointment, cream or mask) of Aloe Vera is Chiefly Promoted, unless Advised by a Medical Professional.

Aloe Vera is orally consumed in various forms, like soft gel capsules (liquid encapsulated in a gelatin-like pellet), capsules, powder, juice, etc. The doses range from 100mg to almost 10,000mg. Aloe Gel is considerably safer than the Latex of Aloe Vera when it comes to Oral Consumption. When consumed in large doses and for a longer period of time, it can be very dangerous causing side-effects like cramps, abdominal pain, diarrhea, blood while urinating, heartburn and pain, etc.

Aloe Vera Injections are also available in some countries to help cure cancer, but yet study has to clarify whether it truly “cures” all types of cancer.

Aloe Vera Drug Interactions:

Here are some drugs that react strong to mild with Aloe Vera in a descending order.

1. Digoxin (Lanoxin) - MAJOR (NOT ADVISABLE)
This drug is majorly used to treat heart-related conditions from Atrial Fibrillation, Cardiogenic Shock, Supraventricular Tachycardia to Heart Failure and many more. Digoxin is taken either orally or injected. The Latex of Aloe Vera when consumed via the mouth is a stimulant laxative which tends to reduce the potassium levels in the human body. Lack of potassium can surge the side-effects of Digoxin (Lanoxin) which are Dizziness, Rapid heartbeat, etc.

2. Warfarin (Coumadin) - MODERATE
arfarin is an anticoagulant (blood thinner) which decreases the formation of blood clots, consumed by patients of heart diseases. Aloe vera not only decreases the clotting but also is a stimulant laxative. It causes diarrhea which further activates the effects of Warfarin, increasing the danger of bleeding.

3. Sevoflurane (Ultane) - MODERATE
Sevoflurane is an anaesthetic used during surgeries. It also reduces blood clotting. Aloe offers the same leading to excessive bleeding during the operation. Hence, it is advised not to take Aloe Vera by mouth for a minimum of 3 weeks before and after the surgery.

4. Medication for Oral Health - MODERATE
Aloe Vera Latex will decrease your body’s ability to absorb medicines, as it is a laxative. Hence, when both are consumed together, the potency of the drug reduces.

5. Anti-Diabetic Drugs - MODERATE
loe Vera, when consumed regularly can lower blood sugar levels. The Diabetic drugs are prescribed for the same purpose. When taken cohesively the blood sugar levels can drop down dangerously leading to hypoglycemia, which may cause you to experience headaches, tremors, nausea, weakness, palpitations, etc. It is necessary to keep a check on your sugar levels and change the dosage accordingly as per the doctor’s guidance.

6. Other Stimulant Laxatives - MODERATE
The Latex is by itself a stimulant laxative when taken by the mouth. Stimulant laxatives work for accelerating the bowel movements and relieving constipation. When one consumes more than just one stimulant laxative, it can lead to diarrhoea, dehydration and loss of minerals.

Here are some other stimulant laxatives frequently used - Bisacodyl, Cascara, Castor Oil, Senna, etc.

7. Diuretics aka Water Pills - MODERATE
Water Pills reduce the potassium levels and so does the Latex of Aloe Vera. When consumed simultaneously, lack of essential potassium in the body can be experienced. Here are some diuretics – Furosemide and Chlorothiazide.

Risks of Aloe Vera:

  • Pregnancy and Breast-Feeding - Pregnant women and mothers practicing breastfeeding must NOT consume Aloe Vera in any form as it has links to miscarriages and even birth defects in Children.
  • High Dosage- Consuming 1gm Aloe Latex per day for long terms can be life-threatening.
  • Cancer Warning - Aloin, the substance which gives Latex its yellow color carries cancer-causing elements observed in lab testing on animals.
  • Colorectal Cancer - The Latex can stain the Colon - the end part of the gut tract causing Colorectal Cancer.
  • Intestinal Conditions, Kidney Failure and Hemorrhoids - If you are suffering from Ulcerative Colitis, or Crohn’s Disease, Aloe latex is not advisable for you especially in high doses. It is known as a bowel irritant, also a stimulant laxative.
  • Allergic to Garlic, Onion and Tulips - People with a medical history of allergies to specifics are at high risks from the application of Aloe Vera, even Topical.
  • Liver Damage - This is uncommon but those who are hypersensitive to Aloe can experience it. Hence, precaution is strongly advised. It is also important to seek professional medical guidance on dosage and timing of your consumption.


The above information is extracted from the internet for knowledge purpose only. We strongly recommend taking any medicine (drug) on the valid prescription or advice of a medical practitioner. 3meds do not accept any responsibility for medical outcome of these medicines.

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