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Cushing's Syndrome - Symptoms, How is it Caused and Treated?

05 September, 2020 Aditya Mishra

Cushing's syndrome is a hormonal disorder caused due to increased levels of the hormone cortisol in the body. It’s also referred to as hypercortisolism. Cortisol comes from your adrenal glands, located at the top of the kidneys. It helps our body:

1)Maintain vital sign

2)Regulate blood glucose

3)Lower inflammation

4)Turn the food you fret energy

But once you have an excessive amount of cortisol, it can throw off your body's other systems.

Most cases of Cushing's syndrome are often cured, though it's going to take a while for your symptoms to ease up.

The chances of having Cushing's syndrome is more frequent in women than in men. It's most frequently seen in people ages 25-40.

Cushing’s Syndrome Causes and Risk Factors

You can get Cushing's syndrome when there’s an excessive amount of cortisol in your body for too long.

1)The most common cause is said to medications called glucocorticoids, also commonly referred to as corticosteroids, steroids, or prednisone. Hence you should consult your doctor or search on online chemist shop Delhi, India to know about the consequences of your medication.

2)These prescription steroids are used for conditions like asthma, atrophic arthritis, lupus, or after a transplant. They’re powerful anti-inflammatory medications. Taking an excessive amount of, for too long, can cause Cushing's syndrome.

3)You can also get Cushing’s syndrome from injectable steroids, like repeated shots for joint pain, bursitis, and back pain.

4)Steroid skin creams, used for eczema and other skin problems can rarely cause Cushing’s Syndrome.

5)A tumor in your pituitary or a tumor within the adrenal glands also can prompt your body to form an excessive amount of cortisol, which may cause Cushing’s.

6)In rare cases, an ACTH-secreting tumor causes Cushing’s syndrome.

7)It's not usually a hereditary condition. In some rare cases, though, people have it because a drag in their genes makes them more likely to urge tumors on their glands.

Cushing’s Syndrome Symptoms

Your case could be different than someone else's, but when the disease is full-blown, common symptoms are:

1) A rounded, rosy face

2) Weight gain, especially within the upper body

3) A fat pad within the upper back or base of the neck (You may hear this called a "buffalo hump.")

4) Thinning skin that's easy to bruise

5) Acne

6) Being very tired

7) Weak muscles, especially when using your shoulders and hip muscles

8) High vital sign

9) High blood glucose levels

10) Depression and anxiety

11) Osteoporosis

12) Kidney stones

13) Sleep problems

14) Extra hair growth on your body and face

15) Irregular periods

16) Low drive and problems having an erection

17) Decreased fertility

Your skin might become thin, heal slowly, and bruise easily. you would possibly get purple or pink stretch marks everywhere your body, especially on your belly, thighs, arms, and chest.

Your bones may get weak. Everyday movements like bending, lifting, or maybe getting out of a chair can cause backaches or breaks in your ribs or spine.

Children with Cushing's syndrome are usually very heavy(obese) and have a tendency to grow slowly.

Cushing’s Syndrome Diagnosis

It might take several appointments to choose your diagnosis.

When you attend your doctor, they'll do a physical exam and ask you questions such as-

1) What symptoms have you ever noticed?

2) When did you initially see them?

3) Does anything make them better? Or worse?

4) Are you feeling more emotional?

5) What medications are you taking?

Your doctor may also recommend a number of these tests to assist screen for Cushing’s syndrome if they think you've got it:

24-hour urinary free cortisol test. This common test collects your urine for twenty-four hours to live what proportion cortisol is in it.

Dexamethasone suppression test- First you’ll take a low-dose steroid pill at 11:00 p.m. Then take a biopsy within the morning to ascertain what proportion cortisol your body still makes.

Late-night salivary cortisol level. This test measures cortisol in your saliva. because the name suggests, these tests happen in the dark.

If you've got Cushing's syndrome, your doctor may refer you to a specialist who will do other blood tests or imaging scans to seek out out what's causing it.

Cushing’s Syndrome Treatment

The first thing your doctor will find out is why you've got an excessive amount of cortisol. which will cause the way to treat your condition.

1) If you've got an excessive amount of cortisol because of taking steroid medicines, your doctor will check to ascertain if you'll slowly lower your dose while still managing your asthma, arthritis, or other condition.

2) you'll need surgery to get rid of a tumor.

3) you'll have radiation alongside surgery if the tumor can’t be completely removed. It also can be used rather than surgery in some cases.

4) Medications to regulate cortisol production could also be an option when surgery and radiation don’t work. These medications can have serious side effects. A doctor can also prescribe medications before surgery in people that are very sick with Cushing’s syndrome. You can buy prescription drugs online Delhi, India.

5) In some cases, the tumor or its treatment will affect other hormones produced by the pituitary or adrenal, and you'll need hormone replacement medication.

Cushing’s Syndrome Complications

Cushing’s syndrome can cause serious health problems and even death if not treated at a time. Problems may include:

1) An attack or stroke

2) Blood clots within the legs or lungs

3) Infections

4) Bone loss and fractures

5) High vital sign

6) High cholesterol

7) Depression or mood changes

8) Loss of memory or trouble concentrating

9) Type 2 diabetes

Conclusion-

Most of the time Cushing’s syndrome is often treated and cured. But if your Cushing's syndrome isn't curable, you'll be wanting to seem for tactics to manage your weight gain, muscle weakness, and tiredness. Partner together with your doctor thereon, and tell your doctor how you are feeling. If you get depressed, it is vital to urge treated for that.